Evaluation of an inactivated infectious bursal disease virus vaccine prepared using a local isolate from Egypt

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An experimental study on early pathogenesis of a very mvirulent isolate of infectious bursal disease virus, employing immunohistochemistry

In this study, immunohistochemistry was used to clarify the early stages of viral kinetics and cycliccourse of IBDV, IR499, which has been described earlier as a very virulent strain (vvIBDV). Fifteen, 4-week-old SPF chickens were inoculated with 10³ EID50 of vvIBDV, IR499, via oculo/nasal route. Five birdsserved as controls, and inoculated with phosphate buffered saline (PBS). The birds were t...

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Isolation, Characterization and Standardization of New Infectious Bursal Disease Virus for Development of a Live Vaccine

Background and Aims: Infectious bursal disease (IBD) is an acute contagious viral disease of birds worldwide. The causative virus induces a persistent immune suppression following destroy B lymphocytes precursors in bursal lymphoid follicles. Vaccination is the main strategy for prevention of the disease in commercial poultry industry. Materials and Methods: To produce a live vaccine against th...

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ژورنال

عنوان ژورنال: Benha Veterinary Medical Journal

سال: 2015

ISSN: 1110-6581

DOI: 10.21608/bvmj.2015.32655